Cell for Raman spectroscopy analysis

Technology description

Due to its low sensitivity, Raman specroscpy requires the use of medium power laser sources in order to attain a good signal-to-noise ratio (S/N) in a short measurment time. In the case the sample is photosensitive, typically the laser power is reduced, causing a significant increase in the measurment time. Furthermore, this approach is sometime insufficient to prevent the sample damaging. The solution to this problem, as described in this patent, is the possibility to perform the Raman measurments on a moving sample, such as each spot on the samples is exposed to the laser beam for a short time. In this way, the probability of thermal- and photo- degradation of the sample is reduced: this also allows using higher laser power, thus reducing the measurement time. The sample is kept under movement by mounting it on small-sized cylindircal sample holder, containing a magnetic element. The movement is generated by an external magnetic stirrer, as commonly found in any chemical lab, easily adaptable to the Raman instrumentation.


1. Raman spectroscopy under operando conditions (Catalysis, Synthesis, etc) [Top. Catal. 61  (2018) 1491]
2. Raman spectroscopy for biological systems
3. Forensic chemistry [Talanta, 209 (2020)  120565]
4. Surface Enhanced Raman Spectroscopy (SERS)

Key advantages
  • Low cost of the device.
  • Easy integration with different Raman instruments and controlled atmosphere measurment cells
  • Decrease of the measurment time
  • Increased applicability of Raman spectroscopy
  • Increased statistical significance of measurments
  • Alessandro Damin
  • Matteo Signorile
  • Francesca Carla Bonino
  • Silvia Bordiga
  • Raffaele Disa
Filing date and application number

Filing date: 11/06/2015

Application number: 11/06/2015



  • Università degli Studi di Torino 
  • DISA